MyBioSource.com's CD8 antibody (allophycocyanin) is a Rat monoclonal antibody. This antibody has been shown to work in applications such as: Flow Cytometry, and Western Blot.
Description
Rat monoclonal CD8 antibody (allophycocyanin)
The 53-6.7 monoclonal antibody reacts with the mouse CD8a molecule. CD8a is an approximately 32-34 kDa cell surface receptor expressed either as a heterodimer with the CD8 beta chain or as a homodimer. A majority of thymocytes and a subpopulation of mature alpha beta TCR T cells express CD8 alphabeta while gamma delta TCR T cells, a subpopulation of intestinal intraepithelial lymphocytes and dendritic cells express CD8 alpha alpha. CD8 binds to MHC class I and through its association with protein tyrosine kinase p56lck plays a role in T cell development and activation of mature T cells